Size Of FBD Sieve

FBD commonly known as a fluid bed or fluidized bed dryer is used in pharma industries for drying products manufactured by a wet granulation process.

A Fluid Bed Dryer has a trolley or detachable bowl in which we add the product for drying by fluidization.

For Fluidization the air enters into the product trolley through the bottom of the FBD trolley so the bottom of the product trolley is perforated.


Dutch Woven Screen

For perforation, a sieve or screen is fitted at the bottom of the FBD product trolley & this sieve or screen is known as Dutch Woven Screen or Dutch Woven sieve.

The sieve or dutch woven screen is attached with the bottom of FBD product trolley with the help of hand-driven screw clumps so it can easily be removed during washing & can be installed later on.


Purpose Of Dutch Woven Screen

The mesh or screen of Fluidized Bed Dryer is constructed in a way that it only allows the air to pass & retains the product inside.

FBD trolley mesh or sieve provides a passage for air & prevents product loss through the bottom of FBD trolley.


Construction Of Dutch Woven 

Screen

As the sieve of the FBD trolley is in direct contact with the product, it is made of SS grade 316L.


Size Of FBD Trolley Sieve

The size of the screen fitted with Fluidized bed dryer trolley is different for different models & sizes of FBD.

Usually, the pore size of the FBD sieve ranges between 100 to 200 microns.

Mesh size is usually written as follows,


  • 24×110

  • 30×150

  • 40×200


The first numbers represent Standard Wire Gauge (SWG) and the second numbers represent sieve size.

Generally  24 × 110 mesh is used & if the particle size is very small then 30 ×150 number or 40 × 200 pore size FBD screen is used.


Also, Read 

Working of fluid bed dryer.


Application of tray dryers in pharmaceuticals.


SOP Of Fluid Bed Dryer


Quality Assurance Interview Questions


SOP For Colloid Mill

Standard Operating Procedure for Colloid Mill.


1.0 Purpose

The purpose of this SOP is to develop a standard procedure for operating the Colloid Mill.


2.0 Scope

This SOP applies to the Colloid Mill used in the liquid manufacturing area of the production section.


3.0 Responsibility

3.1 Machine Operator is responsible for operating the Colloid Mill.


3.2 Manufacturing Pharmacist is responsible for the implementation of this SOP.


3.3 The Head Of Production is responsible for ensuring the implementation of the current SOP.


3.4 Q.A. Officer monitors the compliance of this SOP.


4.0 Procedure

4.1 Area Pharmacist shall ensure that Colloid Mill & all its parts are properly cleaned.


4.2 Assemble the Colloid Mill parts, adjust the hopper in its place and take line clearance from the Quality Assurance officer.


4.3 Close the valve of the hopper & add suspension or slurry to be milled in the hopper as mentioned in BMR.


4.4 Insert the wire plug of the colloid mill into the socket & press the On button.


4.5 Mill the Suspension at specifications mentioned in BMR and collect in the container placed below the discharging end.


4.6 Pass all the suspension through the colloidal mill & at the end press the Off button.


4.7 Remove the wire plug, Affix 'To be cleaned label' and record the activity in the logbook of the colloid mill.


5.0 Abbreviations

5.1 SOP: Standard Operating Procedure

5.2 BMR: Batch Manufacturing Record

5.3 QA: Quality Assurance


Also, Read


SOP For Liquid Transfer Pump


SOP For Propeller Mixer


SOP For Liquid Manufacturing Vessel


SOP For Liquid Transfer Pump

Standard Operating Procedure for Liquid Transfer Pump.


1.0 Purpose

The purpose of this SOP is to develop a standard procedure for operating the Liquid Transfer Pump.


2.0 Scope

This SOP is applicable to the Liquid transfer pump used in the liquid manufacturing area of the production section & bulk liquid dispensing area of the raw material.


3.0 Responsibility

3.1 Machine Operator or dispensing person is responsible for operating the Liquid Transfer Pump.


3.2 Manufacturing Pharmacist or Dispensing Pharmacist is responsible for the implementation of this SOP.


3.3 The Head Of Production/Stores is responsible for ensuring the implementation of the current SOP.


3.4 Q.A. Officer monitors the compliance of this SOP.


4.0 Procedure

4.1 Area Pharmacist shall ensure that the Liquid Transfer Pump & transfer pipes are properly cleaned. 


4.4 Pharmacist shall ensure that the Liquid Transfer Pump & area

 is labeled with product-related labels. 


4.5 Take line clearance from the Quality Assurance officer.


4.5 After line clearance, assemble the transfer pump & connect transfer pipes to the inlet & outlet ports of the liquid transfer pump.


4.6 Connect the other end of inlet pipe to the container/vessel from where the liquid is to be dispensed or transferred.


4.7 Connect outlet pipe to the container/vessel to which liquid is to be delivered.


4.8 Now insert the wire plug of the transfer pump into the socket & press the On button.


4.8 Carefully observe the transfer pipe & its connections for any leakage during the process of transferring  and immediately stop the pump if any leakage is observed.


4.9 Press the Off button when the required quantity is transferred or dispensed & remove the wire plug.


4.1 Affix the 'To be cleaned label' and record the activity in the logbook of the transfer pump.



5.0 Abbreviations

5.1 SOP: Standard Operating Procedure

5.2 BMR: Batch Manufacturing Record

5.3 QA: Quality Assurance


Also, Read

SOP For Propeller Mixer


SOP For Liquid Manufacturing Vessel


SOP For Peristaltic Pump


SOP For Stacking Of Packed Shippers On Pallets


SOP For Cleaning Of Pallets